Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12581613 | 0.84 | CYP3A4 (0.42) | HTTALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL3970026 | 0.83 | MAPK1 (0.53) | HTTALDH1A1SMN1; SMN2TYRMAPK1 | |
| SCHEMBL22609190 | 0.80 | ALOX5 (0.51) | HTTALDH1A1MAPTTYRMAPK1 | |
| SCHEMBL10331729 | 0.79 | ALDH1A1 (0.46) | HTTALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL7196547 | 0.79 | ALOX5 (0.54) | HTTALDH1A1MAPTTYRMAPK1 | |
| SCHEMBL4803729 | 0.77 | HTT (0.50) | HTTALDH1A1MAPTSMN1; SMN2TYR | |
| SCHEMBL2583180 | 0.77 | HTT (0.54) | HTTALDH1A1MAPTSMN1; SMN2TYR | |
| SCHEMBL3185655 | 0.75 | ERN1 (0.52) | ALDH1A1MAPTKDM4EKMT2AGAA | |
| SCHEMBL12581695 | 0.75 | ERN1 (0.45) | ALDH1A1MAPTTYRHPGDKDM4E | |
| SCHEMBL1527069 | 0.75 | BID (0.50) | MAPTTYRKDM4EALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998899-A1 | Use of butylhydroxytoluene for stabilizing of flavones, flavanones or flavonoids, and synergistic mixtures , cosmetic and dermatological preparations containing them | Beiersdorf Aktiengesellschaft (DE) | 2000-05-10 | — | — | EP | disclosed |