Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 4/20 | 0.39 |
| ▸ | FNTB | P49356 | 4/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419778 | 0.87 | HDAC1 (0.48) | HDAC1HDAC8HDAC6SRCFNTA | |
| SCHEMBL7423007 | 0.84 | GRM5 (0.52) | CRBNHDAC1HDAC8HDAC6GRM5 | |
| SCHEMBL8040881 | 0.82 | FNTA (0.45) | FNTAFNTBPGGT1BF10F2 | |
| SCHEMBL7422065 | 0.81 | SRC (0.39) | HDAC1HDAC8HDAC6SRCF10 | |
| SCHEMBL7427696 | 0.80 | HDAC1 (0.41) | HDAC1HDAC8HDAC6FNTAFNTB | |
| SCHEMBL7425114 | 0.78 | GRM5 (0.45) | CRBNGRM5FNTAFNTBPGGT1B | |
| SCHEMBL7419783 | 0.77 | FNTA (0.52) | HDAC1HDAC8HDAC6FNTAFNTB | |
| SCHEMBL7423307 | 0.77 | F10 (0.39) | HDAC1HDAC8HDAC6FNTAFNTB | |
| SCHEMBL2330001 | 0.76 | F2 (0.38) | SRCFNTAFNTBPGGT1BF10 | |
| SCHEMBL8040094 | 0.76 | F2 (0.38) | SRCFNTAFNTBPGGT1BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034093-A | Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-03-07 | — | — | US | disclosed |