Cyclopropane

Cyclopropane

SCHEMBL8040928

C1CC1.NNCC(=O)O

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290730 0.91
SCHEMBL27796812 0.88
Hydrochloric Acid SCHEMBL4062946 0.88
Water SCHEMBL11546193 0.88
Benzene SCHEMBL8598626 0.85 MAOA (0.41)
Water SCHEMBL27890637 0.85
Ethylene SCHEMBL28293069 0.85
Potassium Chloride SCHEMBL28646771 0.78 GRIN2D (0.35)
SCHEMBL9094845 0.72 ALDH1A1 (0.39)
Sarcosine SCHEMBL29066527 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794959-B1 AMINO ACIDS FOR MAKING BETIDES AND METHODS OF SCREENING AND MAKING BETIDE LIBRARIES SALK INST FOR BIOLOGICAL STUDI (US) 2000-04-05 EP disclosed
US-5807986-A GENETIC ENGINEERING THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1998-09-15 US disclosed
US-5681928-A ACYLATION, ALKYLATION OF AN AMINOGLYCINE; INSERTION INTO PEPTIDE THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1997-10-28 US disclosed
EP-0794959-A1 AMINO ACIDS FOR MAKING BETIDES AND METHODS OF SCREENING AND MAKING BETIDE LIBRARIES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1997-09-17 EP disclosed
WO-1996018642-A1 AMINO ACIDS FOR MAKING BETIDES AND METHODS OF SCREENING AND MAKING BETIDE LIBRARIES THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1996-06-20 WO disclosed