Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027749 | 0.89 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4ETDP1LMNA | |
| SCHEMBL8037895 | 0.88 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL8037864 | 0.87 | SMN1; SMN2 (0.58) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL6349020 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL6340707 | 0.83 | KMT2A (0.61) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL6337014 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL8044170 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL6344805 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL8039718 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HSD17B10TSHRMAPK10KMT2A | |
| SCHEMBL8039717 | 0.79 | KMT2A (0.56) | ALDH1A1HSD17B10TSHRMAPK10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |