Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039096 | 0.93 | PYGL (0.42) | KDM4EL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL8025608 | 0.89 | CA12 (0.47) | KDM4EL3MBTL1HPGDALDH1A1TSHR | |
| SCHEMBL8025601 | 0.87 | TRPV1 (0.48) | ALDH1A1PYGL | |
| SCHEMBL8035171 | 0.86 | PYGL (0.45) | KDM4EL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL8035725 | 0.84 | KDM4E (0.43) | KDM4EL3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL8035132 | 0.77 | S1PR1 (0.38) | KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL8023948 | 0.77 | PYGL (0.46) | KDM4EMEN1KMT2APYGL | |
| SCHEMBL8037394 | 0.74 | POLB (0.46) | KDM4EL3MBTL1HPGDALDH1A1POLB | |
| SCHEMBL8040249 | 0.74 | PYGL (0.47) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL8039179 | 0.73 | PYGL (0.46) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |