Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 13/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035171 | 0.82 | PYGL (0.45) | PYGLNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8025608 | 0.81 | CA12 (0.47) | PYGLMAPTKDM4E | |
| SCHEMBL8039185 | 0.80 | PYGL (0.49) | PYGLNPC1RAB9AMAPTMEN1 | |
| SCHEMBL8025601 | 0.80 | TRPV1 (0.48) | PYGLMAPT | |
| SCHEMBL8037235 | 0.80 | SMPD1 (0.45) | PYGLNPC1RAB9AS1PR1KDM4E | |
| SCHEMBL8041247 | 0.79 | HSP90AA1 (0.39) | HSP90AA1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL8039096 | 0.79 | PYGL (0.42) | PYGLMEN1KMT2AKDM4E | |
| SCHEMBL8039179 | 0.77 | PYGL (0.46) | PYGLNPC1RAB9AMAPTS1PR1 | |
| SCHEMBL8041323 | 0.77 | KDM4E (0.45) | PYGLMEN1KMT2AKDM4E | |
| SCHEMBL8040249 | 0.75 | PYGL (0.47) | PYGLMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |