Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPR3 | P17342 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998707 | 0.91 | POLB (0.48) | KMT2AMEN1LMNARAB9AMAPT | |
| SCHEMBL7635490 | 0.82 | ALDH1A1 (0.43) | KMT2AMEN1LMNAALDH1A1NPSR1 | |
| SCHEMBL7639674 | 0.82 | ALDH1A1 (0.43) | KMT2AMEN1LMNAALDH1A1NPSR1 | |
| SCHEMBL7636702 | 0.79 | PPID (0.49) | KMT2AMEN1LMNAALDH1A1NPSR1 | |
| SCHEMBL7636689 | 0.79 | PPID (0.49) | KMT2AMEN1LMNAALDH1A1NPSR1 | |
| SCHEMBL8014867 | 0.76 | FFAR1 (0.50) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6303423 | 0.75 | CA12 (0.41) | ALDH1A1RAB9AMAPT | |
| SCHEMBL8008244 | 0.73 | FFAR1 (0.49) | LMNA | |
| SCHEMBL6302904 | 0.73 | SLC13A5 (0.49) | KMT2AMEN1LMNAALDH1A1CYP2C9 | |
| SCHEMBL6692391 | 0.73 | SLC13A5 (0.49) | KMT2AMEN1LMNAALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |