SCHEMBL8041465

SCHEMBL8041465

Cc1cccc(Cc2cccc(C(=O)O)c2O)c1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.61
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
HSD17B10 Q99714 2/20 0.61
HMGB1 P09429 2/20 0.53
CYP3A4 P08684 2/20 0.49
CYP2C9 P11712 2/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.46
AKR1B10 O60218 1/20 0.46
TRPA1 O75762 1/20 0.46
ABCB11 O95342 1/20 0.46
DHFR P00374 1/20 0.46
LMNA P02545 1/20 0.46
MPO P05164 1/20 0.46
CYP1A2 P05177 1/20 0.46
CHRM1 P11229 1/20 0.46
AKR1B1 P15121 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1396288 0.89 HPGD (0.62) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL2600784 0.87 TSHR (0.56) KDM4EALDH1A1HPGDHSD17B10CYP3A4
SCHEMBL633197 0.86 HMGB1 (0.67) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL29697016 0.86 HMGB1 (0.67) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL11490533 0.85 PTPN1 (0.64) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL1560171 0.81 HMGB1 (0.57) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL9450042 0.81 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL2473330 0.80 HMGB1 (0.56) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL112902 0.80 PTPN1 (0.65) KDM4EALDH1A1HPGDHSD17B10HMGB1
SCHEMBL30612910 0.80 PTPN1 (0.65) KDM4EALDH1A1HPGDHSD17B10HMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0992363-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-04-12 EP disclosed