Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.65 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.65 |
| ▸ | TACR1 | P25103 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30232507 | 0.83 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 | |
| SCHEMBL1201181 | 0.81 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 | |
| SCHEMBL374167 | 0.81 | DUT (0.46) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 | |
| SCHEMBL374107 | 0.81 | OPRM1 (0.46) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL3518260 | 0.80 | SLC6A4 (0.96) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 | |
| SCHEMBL4630111 | 0.80 | SLC6A2 (0.45) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 | |
| SCHEMBL3246807 | 0.79 | TACR1 (0.56) | SLC6A4OPRM1TACR1 | |
| SCHEMBL3408207 | 0.79 | OPRL1 (1.00) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL1513382 | 0.78 | TACR1 (0.54) | SLC6A4OPRM1TACR1 | |
| SCHEMBL3133325 | 0.78 | SLC6A4 (0.76) | SLC6A4SLC6A3SLC6A2OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |