Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427872 | 0.94 | PRKCA (0.51) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL12427909 | 0.91 | PRKCA (0.58) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL12427843 | 0.91 | PRKCA (0.53) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL12427884 | 0.90 | PRKCA (0.53) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL804300 | 0.89 | PRKCA (0.59) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL10283727 | 0.89 | PRKCA (0.51) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL12427797 | 0.89 | PRKCA (0.51) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL12428102 | 0.87 | PRKCA (0.59) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL12427928 | 0.87 | PRKCA (0.59) | PRKCAMMP12NR1I2CCKBRSCN9A | |
| SCHEMBL12427939 | 0.87 | PRKCA (0.49) | PRKCAMMP12NR1I2CCKBRSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | POLI, TERT, ZC3HAV1 | PRKCA 2404/4885MMP12 1013/4885NR1I2 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.