SCHEMBL8041709

SCHEMBL8041709

CCCC=C(C(=O)O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 3/20 0.50
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
CES2 O00748 5/20 0.44
CES1 P23141 5/20 0.44
AKR1C2 P52895 2/20 0.44
AKR1C3 P42330 2/20 0.44
LMNA P02545 1/20 0.43
PTGS2 P35354 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.41
CYP2C9 P11712 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GRIK1 P39086 1/20 0.40
GRIK2 Q13002 1/20 0.40
MTNR1A P48039 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6259485 1.00 AKR1C1 (0.50) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL8041704 1.00 AKR1C1 (0.50) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL2109360 0.90 SMN1; SMN2 (0.53) ALDH1A1CYP1A2CYP3A4KMT2AMEN1
SCHEMBL524133 0.89 CES2 (0.47) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL8157814 0.89 CES2 (0.47) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL597781 0.87 EP300 (0.50) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL597783 0.87 EP300 (0.50) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL14763931 0.87 CES2 (0.45) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL6963015 0.87 CYP3A4 (0.48) AKR1C1ALDH1A1CYP1A2CYP3A4TSHR
SCHEMBL6666634 0.86 EP300 (0.53) AKR1C1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104755556-B Electroconductive polymer/polyanionic complexes organic solvent dispersion, the conductive composition containing the organic solvent dispersion and the conductive film covering as made from the conductive composition 荒川化学工业株式会社 2018-12-14 CN disclosed
CN-104744189-A Method for preparing alpha-aryl acrylic acid by carbon dioxide UNIV CHANGZHOU 2015-07-01 CN disclosed
CN-1278142-A Flavouring materials for use in tea containing beverages UNILEVER PLC (NL) 2000-12-27 CN disclosed
US-6120823-A FOR FLAVORING AND PRESERVING FOODSTUFFS HAVING A WATER ACTIVITY EXCEEDING 0.6 INCLUDING BEVERAGES SUCH AS HERBAL TEAS, JUICES; FOR AMBIENT AND CHILLED STABILITY; NON-HALOGENATED LIPTON, DIVSION OF CONOPCO, INC. (US) 2000-09-19 US disclosed
EP-1026955-A1 FLAVOURING MATERIALS FOR USE IN TEA CONTAINING BEVERAGES UNILEVER PLC (GB) 2000-08-16 EP disclosed
US-6022576-A CONTAINS A SUFFICIENT AMOUNT OF A SELECTED SUBSTITUTED PHENYL FLAVORING/ANTIMICROBIAL COMPOUND TO PREVENT MICROBIAL OUTGROWTH WHILE SIMULTANEOUSLY CONTRIBUTING TO THE PLEASANT FLAVOR OF THE BEVERAGE LIPTON, DIVISION OF CONOPCO, INC. (US) 2000-02-08 US disclosed
WO-1999021432-A1 FLAVOURING MATERIALS FOR USE IN TEA CONTAINING BEVERAGES UNILEVER PLC (GB) 1999-05-06 WO disclosed
US-4743585-A PEPTIDES, HYPOTENSIVE AGENTS, HYPERALDOSTERONISM WARNER-LAMBERT COMPANY (US) 1988-05-10 US disclosed