SCHEMBL8041728

SCHEMBL8041728

C=CC(=O)NC(=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5B Q9UGL1 1/20 0.53
TSHR P16473 3/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LMNA P02545 2/20 0.40
TGM2 P21980 5/20 0.38
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FGFR4 P22455 1/20 0.32
F13A1 P00488 1/20 0.31
TGM1 P22735 1/20 0.31
TGM3 Q08188 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
PSMB11 A5LHX3 1/20 0.30
PSMA7 O14818 1/20 0.30
PSMB1 P20618 1/20 0.30
PSMA1 P25786 1/20 0.30
PSMA2 P25787 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10624801 0.97 KDM5B (0.50) KDM5BTSHRALDH1A1MAPK1TDP1
SCHEMBL7750969 0.85 TSHR (0.48) TSHRALDH1A1MAPK1TDP1LMNA
SCHEMBL639639 0.79
Methacrylic Acid SCHEMBL6231224 0.79 ALDH1A1 (0.39) KDM5BTSHRALDH1A1MAPK1TDP1
SCHEMBL7165464 0.78
SCHEMBL26217 0.78
SCHEMBL2953115 0.77 ALDH1A1 (0.46) TSHRALDH1A1MAPK1TDP1LMNA
SCHEMBL10894224 0.76 TSHR (0.46) KDM5BTSHRALDH1A1MAPK1TDP1
SCHEMBL1317431 0.76 TSHR (0.46) KDM5BTSHRALDH1A1MAPK1TDP1
Ethylene SCHEMBL8621311 0.76 TSHR (0.50) TSHRALDH1A1MAPK1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3318580-B1 AQUEOUS EMULSION COMPOSITION KURARAY CO (JP) 2022-12-28 EP disclosed
CN-107735411-B Aqueous emulsion composition 株式会社可乐丽 2020-11-06 CN disclosed
EP-0863131-B1 Acrylic monomers, polymers thereof and crosslinking compositions DAINIPPON INK & CHEMICALS (JP) 2000-05-17 EP disclosed
EP-0863131-A1 Acrylic monomers, polymers thereof and crosslinking compositions DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-09-09 EP disclosed
EP-0310808-B1 CURABLE COMPOSITIONS AND CORROSION RESISTANT COATINGS PREPARED THEREFROM AMERICAN CYANAMID COMPANY (US) 1992-08-05 EP disclosed
EP-0310808-A1 Curable compositions and corrosion resistant coatings prepared therefrom AMERICAN CYANAMID COMPANY (US) 1989-04-12 EP disclosed
US-4778728-A AMINE-REACTIVE POLYMER OF (METH)ACRYLAMAIDOGLYCOLATE, POLYFUNCTIONAL AMINE CROSSLINKER, BENZOTRIAZOLE OR A DIPYRIDYL AMERICAN CYANAMID COMPANY (US) 1988-10-18 US disclosed