Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025495 | 0.88 | KMT2A (0.48) | KMT2AATMMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8025559 | 0.79 | MAPT (0.37) | KMT2AMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8034312 | 0.77 | TBXA2R (0.38) | — | |
| SCHEMBL8038220 | 0.77 | PPIA (0.42) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL8033845 | 0.77 | ATM (0.56) | KMT2AATMMAPTMEN1POLB | |
| SCHEMBL8036201 | 0.76 | EPHX2 (0.39) | — | |
| SCHEMBL8038463 | 0.76 | EPHX2 (0.39) | — | |
| SCHEMBL8023142 | 0.76 | ALDH1A1 (0.39) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL8035145 | 0.76 | LRRK2 (0.35) | KMT2AMAPTSMN1; SMN2MEN1LMNA | |
| SCHEMBL8037015 | 0.75 | ALDH1A1 (0.45) | KMT2AMAPTSMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |