SCHEMBL8041829

SCHEMBL8041829

C=CCOC(=O)c1cccc(C(=O)OCC=C)c1N

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.73
ALDH1A1 P00352 4/20 0.73
HSD17B10 Q99714 3/20 0.73
TSHR P16473 2/20 0.73
RHOA P61586 1/20 0.43
SNCA P37840 1/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 2/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5339693 0.92 ALDH1A1 (0.77) CYP3A4ALDH1A1HSD17B10TSHRRHOA
SCHEMBL8765881 0.89 ALDH1A1 (0.63) CYP3A4ALDH1A1HSD17B10TSHRRHOA
SCHEMBL2361415 0.89 ALDH1A1 (0.63) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL8992671 0.89 ALDH1A1 (0.63) CYP3A4ALDH1A1HSD17B10TSHRRHOA
SCHEMBL8991912 0.89 ALDH1A1 (0.63) CYP3A4ALDH1A1HSD17B10TSHRRHOA
SCHEMBL8788430 0.88 TSHR (0.61) CYP3A4ALDH1A1HSD17B10TSHRRHOA
SCHEMBL8787505 0.86 ALDH1A1 (0.60) CYP3A4ALDH1A1HSD17B10TSHRMAPT
Ethane SCHEMBL28085459 0.85 CYP3A4 (0.92) CYP3A4ALDH1A1HSD17B10TSHRRHOA
SCHEMBL14780445 0.85 ALDH1A1 (0.58) CYP3A4ALDH1A1HSD17B10TSHRRHOA
SCHEMBL14780440 0.85 ALDH1A1 (0.58) CYP3A4ALDH1A1HSD17B10TSHRRHOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6074797-A MULTILAYER PHOTOSENSITIVE ELEMENTS AND SILICONE RUBBERS TORAY INDUSTRIES, INC. (JP) 2000-06-13 US disclosed
EP-0938028-A1 A precursor of waterless planographic printing plates TORAY INDUSTRIES, INC. (JP) 1999-08-25 EP disclosed
EP-0508682-B1 Antibiotic carbapenem derivatives ZENECA LTD (GB) 1997-07-23 EP disclosed
US-5541178-A THIENAMYCINS ZENECA LIMITED (GB) 1996-07-30 US disclosed
US-5252431-A Light sensitive layer and silicone rubber layer; spraying pressurized liquid on the surface to remove the rubber layer FUJI PHOTO FILM CO., LTD. (JP) 1993-10-12 US disclosed
US-5230989-A Presensitized plate FUJI PHOTO FILM CO., LTD. (JP) 1993-07-27 US disclosed
WO-1992017481-A1 ANTIBIOTIC CARBAPENEM DERIVATIVES ZENECA LTD. (GB) 1992-10-15 WO disclosed
EP-0508682-A1 Antibiotic carbapenem derivatives ZENECA LIMITED (GB) 1992-10-14 EP disclosed
EP-0475384-A1 Spray development process Fuji Photo Film Co., Ltd. (JP) 1992-03-18 EP disclosed
US-4863831-A Photosensitive lithographic plate requiring no dampening water having a gelatin primer layer FUJI PHOTO FILM CO., LTD. (JP) 1989-09-05 US disclosed
US-4861698-A HARDENED GELATIN, SILICONE RUBBER FUJI PHOTO FILM CO., LTD. (JP) 1989-08-29 US disclosed
US-4826752-A Dry photosensitive lithographic plate comprising a silicon rubber layer containing an aromatic aminosilane FUJI PHOTO FILM CO., LTD. (JP) 1989-05-02 US disclosed