Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044230 | 0.85 | RAB9A (0.47) | CPB1USP2HPGDRAB9ANPC1 | |
| SCHEMBL8046882 | 0.84 | RECQL (0.41) | CPB1HPGDRAB9ANPC1TSHR | |
| SCHEMBL8045746 | 0.84 | KMT2A (0.53) | HPGDRAB9ANPC1LMNATSHR | |
| SCHEMBL8042494 | 0.83 | HDAC6 (0.56) | USP2RAB9ANPC1TSHRALDH1A1 | |
| SCHEMBL8051528 | 0.83 | USP2 (0.45) | CPB1USP2HPGDRAB9ANPC1 | |
| SCHEMBL8050456 | 0.83 | RAB9A (0.45) | CPB1USP2HPGDRAB9ANPC1 | |
| SCHEMBL8051906 | 0.83 | RAB9A (0.45) | CPB1USP2HPGDRAB9ANPC1 | |
| SCHEMBL8034049 | 0.82 | TSHR (0.58) | USP2HPGDTSHRHTTALDH1A1 | |
| SCHEMBL8044607 | 0.82 | KMT2A (0.40) | CPB1USP2HPGDRAB9ANPC1 | |
| SCHEMBL8042512 | 0.80 | RAB9A (0.50) | CPB1USP2HPGDRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |