Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3996157 | 0.93 | PTGER4 (0.67) | PTGER4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL25734417 | 0.91 | PTGER4 (0.49) | PTGER4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL24900141 | 0.91 | PTGER4 (0.49) | PTGER4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL24900042 | 0.91 | PTGER4 (0.49) | PTGER4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL22382478 | 0.90 | PTGER4 (0.77) | PTGER4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL3998365 | 0.86 | PTGER4 (0.79) | PTGER4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL25734679 | 0.84 | LRRK2 (0.42) | PTGER4KDM4EALDH1A1LRRK2GLA | |
| SCHEMBL8034115 | 0.83 | HCAR3 (0.53) | PTGER4MAPTALDH1A1HPGDNPC1 | |
| SCHEMBL3764360 | 0.83 | PTGER4 (0.70) | PTGER4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL29052950 | 0.82 | PTGER4 (0.58) | PTGER4MAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |