Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3591993 | 0.83 | MAPT (0.52) | ALDH1A1TBXAS1KDM4ELMNA | |
| SCHEMBL11113395 | 0.77 | TBXAS1 (0.54) | TBXAS1KMT2A | |
| SCHEMBL449373 | 0.76 | TBXAS1 (0.59) | ALDH1A1TBXAS1 | |
| SCHEMBL11277597 | 0.76 | TBXAS1 (0.59) | ALDH1A1TBXAS1 | |
| SCHEMBL49709 | 0.76 | TBXAS1 (0.59) | ALDH1A1TBXAS1 | |
| SCHEMBL534913 | 0.76 | TBXAS1 (0.59) | ALDH1A1TBXAS1 | |
| SCHEMBL534951 | 0.76 | TBXAS1 (0.59) | ALDH1A1TBXAS1 | |
| SCHEMBL534846 | 0.76 | TBXAS1 (0.59) | ALDH1A1TBXAS1 | |
| SCHEMBL535710 | 0.76 | TBXAS1 (0.59) | ALDH1A1TBXAS1 | |
| SCHEMBL9738958 | 0.74 | LMNA (0.50) | ALDH1A1KDM4EXDHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017801-A2 | COMPOSITION AND METHOD FOR ENHANCING PARACELLULAR TRANSPORT ACROSS CELL LAYERS | ELAN CORPORATION, Plc (IE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015649-A2 | COMPOSITION AND METHOD FOR ENHANCING PARACELLULAR TRANSPORT ACROSS CELL LAYERS | ELAN CORPORATION, PLC (IE) | 1999-04-01 | — | — | WO | disclosed |