Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.45 |
| ▸ | TACR1 | P25103 | 5/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23858290 | 0.98 | DRD2 (0.53) | DRD2SLC6A4SLC6A3SLC6A2TACR1 | |
| SCHEMBL12248258 | 0.86 | SLC6A4 (0.52) | DRD2SLC6A4SLC6A3SLC6A2ALDH1A1 | |
| SCHEMBL13971687 | 0.82 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2KCNH2HTR2C | |
| SCHEMBL188283 | 0.81 | SLC6A4 (0.60) | DRD2SLC6A4SLC6A3SLC6A2TACR1 | |
| SCHEMBL3485923 | 0.81 | SLC6A3 (0.68) | DRD2SLC6A4SLC6A3SLC6A2TACR1 | |
| SCHEMBL3246807 | 0.81 | TACR1 (0.56) | SLC6A4TACR1KCNH2 | |
| SCHEMBL373790 | 0.81 | SLC6A4 (0.57) | DRD2SLC6A4SLC6A3SLC6A2TACR1 | |
| SCHEMBL5670347 | 0.81 | SLC6A4 (0.71) | DRD2SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL1002809 | 0.80 | SLC6A4 (0.66) | DRD2SLC6A4SLC6A3SLC6A2TACR1 | |
| Ammonia Solution, Strong SCHEMBL7048227 | 0.80 | TACR1 (0.40) | DRD2SLC6A4SLC6A3SLC6A2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050248-A1 | SUBSTITUTED PIPERIDINO-DIHYDROTHIENOPYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |