SCHEMBL8042343

SCHEMBL8042343

C=CC[S+]([O-])c1ccccc1C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.44
ALDH1A1 P00352 6/20 0.39
HPGD P15428 5/20 0.39
MAPT P10636 3/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP3A4 P08684 1/20 0.38
METAP2 P50579 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
BCAT2 O15382 1/20 0.36
PARP1 P09874 1/20 0.35
HTT P42858 1/20 0.35
LMNA P02545 1/20 0.34
GAA P10253 2/20 0.34
USP2 O75604 1/20 0.34
CTNNB1 P35222 1/20 0.33
CYP1A2 P05177 1/20 0.33
AGTR1 P30556 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8179330 0.85 ALDH1A1 (0.42) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL8055106 0.78 ALDH1A1 (0.42) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL8042279 0.75 MAPT (0.42) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL8054057 0.74 HTT (0.44) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL11085208 0.74 ACHE (0.37) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL10616675 0.74 ALDH1A1 (0.34) ALDH1A1TSHRHSD17B10CYP3A4MEN1
SCHEMBL8042332 0.73 KDM4E (0.42) KDM4EALDH1A1MAPTTSHRHSD17B10
SCHEMBL8057920 0.73 CYP3A4 (0.47) KDM4EALDH1A1HPGDMAPTTSHR
SCHEMBL6228527 0.72 KDM4E (0.47) KDM4EALDH1A1HPGDMAPTTSHR
Allyl Alcohol SCHEMBL29155882 0.71 KDM4E (0.54) KDM4EALDH1A1HPGDMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751123-B1 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS (JP) 2000-05-10 EP claimed
US-5744609-A REACTING AN ALKYLTHIOBENZAMIDE WITH A HALOGEN IN A HETEROGENOUS SOLVENT TO GIVE ALKYLSULFURYLBENZAMIDES INTERMEDIATES; USEFUL ANTIBACTERIAL AND ANTIFUNGAL AGENT SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-28 US claimed
EP-0751123-A2 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-01-02 EP claimed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP claimed
JP-7145143-A None JP disclosed
CN-1086693-C Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICAL CO LTD (JP) 2002-06-26 CN disclosed
CN-1086693-C Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICAL CO LTD (JP) 2002-06-26 CN disclosed
EP-0751123-B1 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS (JP) 2000-05-10 EP disclosed
EP-0751123-B1 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS (JP) 2000-05-10 EP disclosed
CN-1215722-A Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1999-05-05 CN disclosed
CN-1215721-A Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1999-05-05 CN disclosed
CN-1215721-A Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1999-05-05 CN disclosed
EP-0657438-A3 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones. SUMITOMO SEIKA CHEMICALS (JP) 1995-10-11 EP disclosed
CN-1107837-A Process for producing alkylsulfinylbenzamides and 1, 2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1995-09-06 CN disclosed
CN-1107837-A Process for producing alkylsulfinylbenzamides and 1, 2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1995-09-06 CN disclosed
CN-1107837-A Process for producing alkylsulfinylbenzamides and 1, 2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1995-09-06 CN disclosed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP disclosed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP disclosed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP disclosed
JP-H07145143-A PRODUCTION OF ALKYLSULFINYLBENZAMIDES SUMITOMO SEIKA CHEM CO LTD 1995-06-06 JP disclosed