SCHEMBL8042468

SCHEMBL8042468

O=C(O)C=COc1ccc(O)cc1C=CC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.53
BACE1 P56817 2/20 0.51
CAPN1 P07384 1/20 0.49
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA4 P22748 2/20 0.44
TYR P14679 2/20 0.44
CA12 O43570 1/20 0.44
AKR1B10 O60218 1/20 0.44
ESR1 P03372 1/20 0.44
CA3 P07451 1/20 0.44
PKM P14618 1/20 0.44
AKR1B1 P15121 1/20 0.44
CA6 P23280 1/20 0.44
DPP4 P27487 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
ESR2 Q92731 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4683657 0.82 BACE1 (0.74) MIFBACE1CAPN1CA1CA2
SCHEMBL4683661 0.82 BACE1 (0.74) MIFBACE1CAPN1CA1CA2
SCHEMBL344709 0.79 BACE1 (0.54) MIFBACE1CAPN1CA1CA2
SCHEMBL344708 0.79 BACE1 (0.54) MIFBACE1CAPN1CA1CA2
SCHEMBL344776 0.76 PTGER4 (0.70) BACE1PKMALDH1A1KDM4EPTGER1
SCHEMBL344775 0.76 PTGER4 (0.70) BACE1PKMALDH1A1KDM4EPTGER1
SCHEMBL344638 0.75 ALDH1A1 (0.64) MIFBACE1CA1CA2CA4
SCHEMBL344639 0.75 ALDH1A1 (0.64) MIFBACE1CA1CA2CA4
SCHEMBL29763068 0.75 ALDH1A1 (0.64) MIFBACE1CA1CA2CA4
SCHEMBL3650396 0.74 JUN (0.38) ESR1ALDH1A1KDM4EHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762208-B1 Light sensitive composition KONISHIROKU PHOTO IND (JP) 2000-04-12 EP disclosed
US-5773194-A PHOTOSENSITIVITY; DURABILITY KONICA CORPORATION (JP) 1998-06-30 US disclosed
EP-0762208-A2 Light sensitive composition, presensitized lithographic printing plate and image forming method employing the printing plate KONICA CORPORATION (JP) 1997-03-12 EP disclosed