Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033612 | 0.81 | HDAC6 (0.43) | RAB9AHSD17B10ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8049875 | 0.81 | GRK6 (0.49) | RAB9AHSD17B10ALDH1A1LMNAKDM4E | |
| SCHEMBL8032616 | 0.79 | SMN1; SMN2 (0.54) | RAB9AHSD17B10ALDH1A1LMNAKDM4E | |
| SCHEMBL8033698 | 0.76 | SMN1; SMN2 (0.42) | RAB9AHSD17B10ALDH1A1KDM4ECYP2C9 | |
| SCHEMBL8044797 | 0.75 | HDAC6 (0.41) | RAB9AHSD17B10SMN1; SMN2NPC1TP53 | |
| SCHEMBL1685094 | 0.75 | SMN1; SMN2 (0.59) | RAB9AHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL8033779 | 0.74 | EGLN1 (0.49) | RAB9AHSD17B10ALDH1A1LMNAKDM4E | |
| SCHEMBL8043076 | 0.73 | TP53 (0.44) | RAB9AHSD17B10ALDH1A1LMNAKDM4E | |
| SCHEMBL8033858 | 0.73 | ADORA2A (0.49) | RAB9AHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL8050490 | 0.73 | CCNE1 (0.41) | RAB9AHSD17B10ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |