SCHEMBL8042570

SCHEMBL8042570

CCCCCCCCCCCCCCCCCCCCCC[NH+](C)CCCCCCCCCCCCCCCCCCCCCC.Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.41
TSHR P16473 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22689573 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL30958372 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL2697055 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL817218 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL2695290 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL19950764 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL2694955 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL16715271 1.00 DNM1 (0.41) DNM1TSHRTHRB
SCHEMBL23754739 0.93 DNM1 (0.36) DNM1
SCHEMBL30472259 0.93 DNM1 (0.36) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889912-B1 HIGHLY SOLUBLE OLEFIN POLYMERIZATION CATALYST ACTIVATOR DOW CHEMICAL CO (US) 2000-07-12 EP claimed
US-10730964-B2 Method of making an olefin polymerization catalyst activator Dow GlobalTechnologies LLC (US) 2020-08-04 US disclosed
US-20180201696-A1 METHOD OF MAKING AN OLEFIN POLYMERIZATION CATALYST ACTIVATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-19 US disclosed
US-9951153-B2 Method of making an olefin polymerization catalyst activator DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-24 US disclosed
EP-2880039-B1 METHOD OF MAKING AN OLEFIN POLYMERIZATION CATALYST ACTIVATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2017-01-04 EP disclosed
US-20150203602-A1 METHOD OF MAKING AN OLEFIN POLYMERIZATION CATALYST ACTIVATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-23 US disclosed
EP-2880039-A1 METHOD OF MAKING AN OLEFIN POLYMERIZATION CATALYST ACTIVATOR Dow Global Technologies LLC (US) 2015-06-10 EP disclosed
WO-2014022461-A1 METHOD OF MAKING AN OLEFIN POLYMERIZATION CATALYST ACTIVATOR DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-06 WO disclosed
US-6121185-A A CATALYST USEFUL FOR POLYMERIZATION OF ADDITION POLYMERIZABLE MONOMERS COMPRISING A GROUP 4 METAL COMPLEX AND A CATALYST AND A CATALYST ACTIVATOR COMPRISING BRONSTED ACID CATION CAPABLE OF DONATING A PROTON AND AN INERT ANION THE DOW CHEMICAL COMPANY (US) 2000-09-19 US disclosed
EP-0889912-B1 HIGHLY SOLUBLE OLEFIN POLYMERIZATION CATALYST ACTIVATOR DOW CHEMICAL CO (US) 2000-07-12 EP disclosed
US-5919983-A COMPRISING A CATION WHICH IS A BRONSTED ACID CAPABLE OF DONATING A PROTON AND AN INERT, COMPATIBLE, NONCOORDINATING ANION THE DOW CHEMICAL COMPANY (US) 1999-07-06 US disclosed
EP-0889912-A1 HIGHLY SOLUBLE OLEFIN POLYMERIZATION CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1999-01-13 EP disclosed
WO-1997035893-A1 HIGHLY SOLUBLE OLEFIN POLYMERIZATION CATALYST ACTIVATOR THE DOW CHEMICAL COMPANY (US) 1997-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10730964-B2 Method of making an olefin polymerization catalyst activator POF1B, BRPF1, PHF2 DNM1 2791/4885TSHR 1743/4885THRB 2433/4885
US-20180201696-A1 METHOD OF MAKING AN OLEFIN POLYMERIZATION CATALYST ACTIVATOR POF1B, BRPF1, PHF2 DNM1 2791/4885TSHR 1743/4885THRB 2433/4885
US-20150203602-A1 METHOD OF MAKING AN OLEFIN POLYMERIZATION CATALYST ACTIVATOR POF1B, BRPF1, PHF2 DNM1 2791/4885TSHR 1743/4885THRB 2433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.