Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589151 | 0.81 | EPHX1 (0.45) | EPHX1KCNH2KCNJ1MAOAMAOB | |
| SCHEMBL28898677 | 0.78 | EPHX1 (0.36) | EPHX1HRH3 | |
| SCHEMBL8040937 | 0.78 | MEN1 (0.39) | EPHX1MAOAMAOBHRH3 | |
| SCHEMBL8040010 | 0.78 | ALDH1A1 (0.42) | EPHX1KCNH2MAOBNPC1RAB9A | |
| SCHEMBL8464214 | 0.78 | EPHX1 (0.47) | EPHX1KCNH2NPC1RAB9AHRH3 | |
| SCHEMBL8042890 | 0.78 | HRH3 (0.45) | EPHX1NPC1RAB9ACYP2A6HRH3 | |
| SCHEMBL3480912 | 0.78 | ACACB (0.37) | — | |
| SCHEMBL934587 | 0.78 | HTT (0.49) | EPHX1NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL8039386 | 0.77 | FFAR1 (0.38) | EPHX1KCNH2MAOAMAOBNPC1 | |
| SCHEMBL8046332 | 0.77 | DAO (0.41) | KCNH2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0675187-B1 | Liquid crystalline compounds and liquid crystal composition | CHISSO CORP (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |
| EP-0675187-A2 | Liquid crystalline compounds and liquid crystal composition | Chisso Corporation (JP) | 1995-10-04 | — | — | EP | disclosed |