Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.53 |
| ▸ | CNR1 | P21554 | 5/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042574 | 1.00 | CNR2 (0.53) | CNR2CNR1MGLLRPA1HDAC3 | |
| SCHEMBL8042546 | 0.77 | CNR2 (0.85) | CNR2CNR1 | |
| SCHEMBL8039725 | 0.77 | CNR2 (0.85) | CNR2CNR1 | |
| SCHEMBL8046115 | 0.74 | RPA1 (0.63) | MGLLRPA1HDAC3HDAC4HDAC1 | |
| SCHEMBL8369218 | 0.74 | RPA1 (0.51) | CNR2CNR1MGLLRPA1HDAC3 | |
| Hydrochloric Acid SCHEMBL8369220 | 0.73 | RPA1 (0.62) | MGLLRPA1HDAC3HDAC4HDAC1 | |
| SCHEMBL8366452 | 0.73 | RPA1 (0.50) | CNR2CNR1MGLLRPA1HDAC3 | |
| SCHEMBL8368094 | 0.71 | HDAC3 (0.50) | CNR2CNR1MGLLRPA1HDAC3 | |
| SCHEMBL8366637 | 0.70 | HDAC3 (0.42) | CNR2CNR1MGLLRPA1HDAC3 | |
| Sr-144528 SCHEMBL1432281 | 0.69 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868420-B1 | 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY | SANOFI SYNTHELABO (FR) | 2000-03-29 | — | — | EP | disclosed |
| EP-0885889-A2 | Process for the preparation of pyrazole-3-carboxylic acids | SANOFI (FR) | 1998-12-23 | — | — | EP | disclosed |