Sr-144528

Sr-144528

SCHEMBL1432281

Cc1ccc(Cn2nc(C(=O)NC3C(C)(C)C4CC[C@@]3(C)C4)cc2-c2ccc(Cl)c(C)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 18/20 1.00
▸ CNR1 P21554 6/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sr-144528 SCHEMBL1546003 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL14355050 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL8137029 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL8039660 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL8313006 1.00 CNR2 (1.00) CNR2CNR1
Sr-144528 SCHEMBL19551517 1.00 CNR2 (1.00) CNR2CNR1
SCHEMBL13883212 0.94 CNR2 (0.88) CNR2CNR1
SCHEMBL13926164 0.94 CNR2 (0.88) CNR2CNR1
SCHEMBL15377558 0.92 CNR2 (0.85) CNR2CNR1
SCHEMBL8042546 0.92 CNR2 (0.85) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008027442-A2 ABUSE DETERRENT ORAL PHARMACEUTICAL FORMULATIONS OF OPIOID AGONISTS AND METHOD OF USE THERAQUEST BIOSCIENCES, LLC (US) 2008-03-06 — — WO claimed
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators SOLVAY PHARMACEUTICALS GMBH (DE) 2007-11-01 — — US claimed
US-20060160776-A1 Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage PHARMACIA CORPORATION 2006-07-20 — — US claimed
WO-2004105699-A2 COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CANNABINOID AGENT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE PHARMACIA CORPORATION (US) 2004-12-09 — — WO claimed
US-12274727-B2 Cannabigerol (CBG) products and methods of use Bzelet Health Systems, Inc. (US) 2025-04-15 — — US disclosed
US-20240180987-A1 CANNABIGEROL (CBG) PRODUCTS AND METHODS OF USE BAZELET HEALTH SYSTEMS INC (US) 2024-06-06 — — US disclosed
US-11890311-B1 Cannabigerol (CBG) products and methods of use Bazelet Health Systems, Inc. (US) 2024-02-06 — — US disclosed
US-10894069-B2 Topical antiviral formulations and methods of using the same MCELVANY CHRISTOPHER A (US) 2021-01-19 — — US disclosed
US-20200230187-A1 TOPICAL ANTIVIRAL FORMULATIONS AND METHODS OF USING THE SAME MCELVANY CHRISTOPHER A (US) 2020-07-23 — — US disclosed
EP-2501669-B1 ARYLATED CAMPHENES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) 2018-01-24 — — EP disclosed
US-9365534-B2 Arylated camphenes, processes for their preparation and uses thereof YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2016-06-14 — — US disclosed
US-9326927-B2 Use of cannabinoid compounds for stimulating melanogenesis L'OREAL (FR) 2016-05-03 — — US disclosed
US-20080206161-A1 QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF FOAMIX PHARMACEUTICALS LTD. (IL) 2008-08-28 — — US disclosed
US-20080063607-A1 Oleaginous pharmaceutical and cosmetic foam FOAMIX LTD 2008-03-13 — — US disclosed
WO-2008027442-A2 ABUSE DETERRENT ORAL PHARMACEUTICAL FORMULATIONS OF OPIOID AGONISTS AND METHOD OF USE THERAQUEST BIOSCIENCES, LLC (US) 2008-03-06 — — WO disclosed
US-20070292461-A1 Oleaginous pharmaceutical and cosmetic foam FOAMIX LTD. (IL) 2007-12-20 — — US disclosed
US-20060160776-A1 Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage PHARMACIA CORPORATION 2006-07-20 — — US disclosed
WO-2004105699-A2 COMPOSITIONS OF A CYCLOOXYGENASE-2 SELECTIVE INHIBITOR AND A CANNABINOID AGENT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DAMAGE PHARMACIA CORPORATION (US) 2004-12-09 — — WO disclosed
EP-0868420-B1 3-PYRAZOLECARBOXAMIDE DERIVATIVES HAVING CANNABINOID RECEPTOR AFFINITY SANOFI SYNTHELABO (FR) 2000-03-29 — — EP disclosed
EP-0885889-A2 Process for the preparation of pyrazole-3-carboxylic acids SANOFI (FR) 1998-12-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206161-A1 QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF NR5A1, CYP17A1, LIPA CNR2 723/4885CNR1 580/4885
US-20070292461-A1 Oleaginous pharmaceutical and cosmetic foam LIPA, LIPC, PLIN3 CNR2 413/4885CNR1 382/4885
US-20070254863-A1 Use of CBx cannabinoid receptor modulators as potassium channel modulators CNR2, CNR1, KCNN1 CNR2 1/4885CNR1 2/4885
US-20080063607-A1 Oleaginous pharmaceutical and cosmetic foam LIPA, LIPC, PLIN3 CNR2 413/4885CNR1 382/4885
US-20060160776-A1 Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage CNR2, CNR1, PTGS2 CNR2 1/4885CNR1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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