Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH4 | P08319 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21987001 | 0.90 | GNAI3 (0.55) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL5645562 | 0.87 | GNAI3 (0.53) | GNAI3GNAO1GNAI1ANPEPERAP2 | |
| SCHEMBL1679033 | 0.84 | ADH1B (0.59) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1679102 | 0.84 | ADH1B (0.59) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1678544 | 0.84 | ADH1B (0.59) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1678148 | 0.82 | ADH1B (0.56) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1678338 | 0.82 | ADH1B (0.56) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1679343 | 0.82 | ADH1B (0.56) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL1679662 | 0.82 | ADH1B (0.55) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL25047164 | 0.79 | ADH1B (0.59) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071707-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE & INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2009-06-11 | — | — | WO | disclosed |