SCHEMBL8042831

SCHEMBL8042831

Fc1ccc(CCCCC(C2CCCCC2)C2CCCCC2)cc1F

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
DPP4 P27487 1/20 0.37
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
NPC1 O15118 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
EPHX1 P07099 1/20 0.33
NUDT1 P36639 1/20 0.33
BACE1 P56817 1/20 0.33
DAO P14920 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046295 0.89 ALDH1A1 (0.42) ALDH1A1HTTMEN1KMT2ADPP4
SCHEMBL8046386 0.85 DPP4 (0.36) DPP4EPHX1
SCHEMBL8040022 0.84 DPP4 (0.35) DPP4EPHX1
SCHEMBL8042938 0.81 RARB (0.35) DPP4RAB9ANPC1EPHX1
SCHEMBL8466846 0.80 EPHX1 (0.43) MEN1KMT2ARAB9ANPC1SLC6A2
SCHEMBL8042732 0.80 DPP4 (0.36) DPP4EPHX1
SCHEMBL28236690 0.78 CYP17A1 (0.41) ALDH1A1HTTMEN1KMT2ADPP4
SCHEMBL8042919 0.78 DPP4 (0.31) DPP4
SCHEMBL9808363 0.74 KDM4E (0.40) DPP4RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL8046332 0.73 DAO (0.41) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727473-B1 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element CHISSO CORP (JP) 2000-01-12 EP disclosed
EP-0675187-B1 Liquid crystalline compounds and liquid crystal composition CHISSO CORP (JP) 1999-09-15 EP disclosed
US-5833879-A LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES CHISSO CORPORATION (JP) 1998-11-10 US disclosed
US-5670085-A Liquid crystalline compound and liquid crystal CHISSO CORPORATION (JP) 1997-09-23 US disclosed
EP-0727473-A2 Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element Chisso Corporation (JP) 1996-08-21 EP disclosed
US-5534187-A CONTAINING CYCLOHEXANE RING CHISSO CORPORATION (JP) 1996-07-09 US disclosed
EP-0675187-A2 Liquid crystalline compounds and liquid crystal composition Chisso Corporation (JP) 1995-10-04 EP disclosed