Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | BRS3 | P32247 | 1/20 | 0.30 |
| ▸ | NMT2 | O60551 | 2/20 | 0.30 |
| ▸ | NMT1 | P30419 | 2/20 | 0.30 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046487 | 0.91 | HRH3 (0.37) | HRH3CTSCCXCR4DPP4F10 | |
| SCHEMBL8046386 | 0.86 | DPP4 (0.36) | DPP4EPHX1C3AR1 | |
| SCHEMBL8040022 | 0.85 | DPP4 (0.35) | DPP4EPHX1C3AR1 | |
| SCHEMBL8042732 | 0.82 | DPP4 (0.36) | DPP4EPHX1C3AR1 | |
| SCHEMBL8042831 | 0.81 | ALDH1A1 (0.40) | DPP4NPC1RAB9AEPHX1 | |
| SCHEMBL28236690 | 0.80 | CYP17A1 (0.41) | HRH3DPP4NPC1RAB9AHRH4 | |
| SCHEMBL8466846 | 0.76 | EPHX1 (0.43) | HRH3NPC1RAB9AEPHX1 | |
| SCHEMBL8042783 | 0.75 | DPP4 (0.38) | DPP4EPHX1C3AR1 | |
| SCHEMBL19720332 | 0.75 | GPR84 (0.39) | HRH3HRH4MAOBBRS3 | |
| SCHEMBL8029152 | 0.72 | SCN9A (0.41) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727473-B1 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0727473-A2 | Liquid crystaline alkynyltolan compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1996-08-21 | — | — | EP | disclosed |