Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 8/20 | 0.39 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033666 | 0.88 | PTGS2 (0.45) | PTGS2PTGS1TSHRHSD17B10KDM4E | |
| SCHEMBL8043392 | 0.88 | TSHR (0.47) | PTGS2TSHRHSD17B10KDM4ENPSR1 | |
| SCHEMBL8042335 | 0.87 | TSHR (0.47) | PTGS2TSHRHSD17B10KDM4ENPSR1 | |
| SCHEMBL8043099 | 0.87 | TSHR (0.57) | TSHRHSD17B10KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL8043009 | 0.85 | HSD17B10 (0.48) | TSHRHSD17B10KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL8050259 | 0.85 | NPSR1 (0.48) | PTGS2TSHRHSD17B10KDM4ENPSR1 | |
| SCHEMBL8033968 | 0.85 | TSHR (0.44) | PTGS2TSHRHSD17B10KDM4ENPSR1 | |
| SCHEMBL8042795 | 0.83 | TSHR (0.47) | TSHRHSD17B10KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL8043664 | 0.81 | TSHR (0.48) | PTGS2PTGS1TSHRHSD17B10KDM4E | |
| SCHEMBL8047148 | 0.81 | TSHR (0.49) | PTGS2TSHRHSD17B10KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |