Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713488 | 0.78 | LMNA (0.37) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL8051506 | 0.77 | ALDH1A1 (0.53) | LMNAMAPTALDH1A1HPGDGAA | |
| SCHEMBL8034052 | 0.73 | LMNA (0.59) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL8043175 | 0.73 | LMNA (0.44) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL8043293 | 0.72 | LMNA (0.46) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL8032520 | 0.72 | SMN1; SMN2 (0.44) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL10815738 | 0.71 | LMNA (0.56) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL8051890 | 0.71 | HSP90AA1 (0.48) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL10816690 | 0.71 | LMNA (0.51) | LMNAPDE10AMAPTALDH1A1HPGD | |
| SCHEMBL8034036 | 0.69 | PSMB8 (0.47) | LMNAPDE10AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |