Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8029697 | 0.90 | EDNRB (0.53) | EDNRBEDNRA | |
| SCHEMBL8902335 | 0.85 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL8039429 | 0.83 | EDNRA (0.55) | EDNRBEDNRA | |
| SCHEMBL8041521 | 0.82 | EDNRB (0.51) | EDNRBEDNRA | |
| SCHEMBL8900846 | 0.80 | EDNRA (0.81) | EDNRBEDNRA | |
| SCHEMBL6322272 | 0.79 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL8900951 | 0.75 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL6322279 | 0.75 | EDNRB (0.62) | EDNRBEDNRA | |
| SCHEMBL4712914 | 0.72 | MAPK8 (0.70) | EDNRBEDNRA | |
| SCHEMBL8547246 | 0.72 | EDNRA (0.81) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075037-A | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-06-13 | — | — | US | disclosed |