Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | MB | P02144 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861674 | 0.82 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL1633802 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL10585737 | 0.76 | SMN1; SMN2 (0.67) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL2615418 | 0.76 | KMT2A (0.81) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL1753885 | 0.76 | KMT2A (0.81) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL3818831 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL11158565 | 0.75 | MAPT (0.83) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL16692667 | 0.75 | TGM2 (0.65) | — | |
| SCHEMBL31499845 | 0.75 | MEN1 (0.46) | KMT2AMEN1ALDH1A1CYP1A1RAB9A | |
| SCHEMBL16692704 | 0.75 | AKR1C3 (0.41) | SMN1; SMN2L3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601235-B1 | BICYCLIC HETEROARYL DERIVATIVES, PREPARATION AND THERAPEUTIC USES THEREOF | XWPHARMA LTD (KY) | 2026-03-04 | — | — | EP | disclosed |
| US-11639337-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XWPharma Ltd. (KY) | 2023-05-02 | — | — | US | disclosed |
| US-20220298127-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | XWPharma Ltd. (KY) | 2022-09-22 | — | — | US | disclosed |
| CN-115025086-A | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-09-09 | — | — | CN | disclosed |
| US-11401249-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XWPharma Ltd. (KY) | 2022-08-02 | — | — | US | disclosed |
| CN-110709386-B | Bicyclic heteroaryl derivatives, their preparation and use | 凯瑞康宁生物工程（武汉）有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112021322-B | Compositions and methods for controlling pests | 住友化学株式会社 | 2022-04-01 | — | — | CN | disclosed |
| US-20210094925-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | XWPharma Ltd. (KY) | 2021-04-01 | — | — | US | disclosed |
| US-10882832-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | XW LABORATORIES INC. (KY) | 2021-01-05 | — | — | US | disclosed |
| CN-112021322-A | Compositions and methods for controlling pests | 住友化学株式会社 | 2020-12-04 | — | — | CN | disclosed |
| WO-2014119672-A1 | PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD | 住友化学株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014119670-A1 | PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD | 住友化学株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014119679-A1 | PEST-CONTROL METHOD | 住友化学株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014119699-A1 | PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD | 住友化学株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014119674-A1 | PEST-CONTROL COMPOSITION AND PEST-CONTROL METHOD | 住友化学株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |
| US-20140194290-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-07-10 | — | — | US | disclosed |
| WO-2013018928-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-07 | — | — | WO | disclosed |
| US-6140528-A | ALKYL PENTAFLUOROSULFANYL-SUBSTITUTED-BENZOATES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-10-31 | — | — | US | disclosed |
| US-6013805-A | USED AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5849928-A | Herbicidal isoxazole and 2-cyano-1,3-dione compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298127-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | GRIN2A, GRIN2C, GRIN3A | SMN1; SMN2 2428/4885HTT 272/4885L3MBTL1 4702/4885 |
| US-10882832-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | SMN1; SMN2 2428/4885HTT 272/4885L3MBTL1 4702/4885 |
| US-11401249-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | SMN1; SMN2 2428/4885HTT 272/4885L3MBTL1 4702/4885 |
| US-20140194290-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | NR0B1, NR4A1, NR2C2 | SMN1; SMN2 1925/4885HTT 1417/4885L3MBTL1 243/4885 |
| US-11639337-B2 | Bicyclic heteroaryl derivatives and preparation and uses thereof | GRIN2A, GRIN2C, GRIN3A | SMN1; SMN2 2428/4885HTT 272/4885L3MBTL1 4702/4885 |
| US-20210094925-A1 | BICYCLIC HETEROARYL DERIVATIVES AND PREPARATION AND USES THEREOF | GRIN2A, GRIN2C, GRIN3A | SMN1; SMN2 2428/4885HTT 272/4885L3MBTL1 4702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.