Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.47 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049340 | 0.87 | SOAT1 (0.45) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL8041447 | 0.87 | SOAT2 (0.47) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL8049433 | 0.86 | SOAT2 (0.46) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL8042243 | 0.86 | SOAT2 (0.46) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL9446292 | 0.84 | SOAT2 (0.57) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL9446304 | 0.84 | SOAT2 (0.57) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL668293 | 0.81 | SOAT2 (0.57) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL9446282 | 0.78 | SOAT2 (0.52) | SOAT1SOAT2ACAT1ALDH1A1MAPT | |
| SCHEMBL8417196 | 0.78 | SOAT2 (0.42) | SOAT1SOAT2ACAT1ALDH1A1LMNA | |
| SCHEMBL893576 | 0.78 | SOAT1 (0.47) | SOAT1SOAT2ACAT1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874812-B1 | NOVEL 2,3,5-TRIMETHYL-4-HYDROXY ANILIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | PF MEDICAMENT (FR) | 2000-04-05 | — | — | EP | disclosed |