Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.52 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446322 | 0.98 | SOAT2 (0.50) | SOAT2ACAT1SOAT1CNR1ALDH1A1 | |
| SCHEMBL9446304 | 0.93 | SOAT2 (0.57) | SOAT2ACAT1SOAT1ALDH1A1MAPT | |
| SCHEMBL9446292 | 0.93 | SOAT2 (0.57) | SOAT2ACAT1SOAT1ALDH1A1MAPT | |
| SCHEMBL9446316 | 0.81 | HPGD (0.59) | SOAT2ACAT1SOAT1CNR1ALDH1A1 | |
| SCHEMBL9446321 | 0.79 | ALDH1A1 (0.63) | SOAT2SOAT1CNR1ALDH1A1GLA | |
| SCHEMBL9446298 | 0.78 | SOAT2 (0.45) | SOAT2ACAT1SOAT1CNR1ALDH1A1 | |
| SCHEMBL9446329 | 0.78 | ALDH1A1 (0.64) | SOAT2SOAT1CNR1ALDH1A1GLA | |
| SCHEMBL8043445 | 0.75 | SOAT2 (0.69) | SOAT2ACAT1SOAT1 | |
| SCHEMBL8042246 | 0.74 | SOAT2 (0.67) | SOAT2ACAT1SOAT1THRB | |
| SCHEMBL8416104 | 0.74 | SOAT2 (0.67) | SOAT2ACAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | claimed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | claimed |
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |