Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033105 | 0.75 | POLB (0.33) | ALDH1A1RAB9A | |
| SCHEMBL8049429 | 0.70 | — | — | |
| SCHEMBL8502488 | 0.69 | PTGS1 (0.41) | MEN1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL8042516 | 0.69 | — | — | |
| SCHEMBL8032506 | 0.68 | — | — | |
| SCHEMBL8032529 | 0.67 | GAA (0.36) | MEN1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL8048051 | 0.67 | PTGS1 (0.32) | MEN1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL8043482 | 0.66 | SMN1; SMN2 (0.34) | MEN1ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL8043479 | 0.66 | — | — | |
| SCHEMBL8032871 | 0.66 | FBP1 (0.40) | ALDH1A1MAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |