Phenyl Propionic Acid

Phenyl Propionic Acid

SCHEMBL8043510

CCOC(=O)CCc1cccc(I)c1.O=C(O)CCc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
CYP4F2 P78329 2/20 0.51
CYP4A11 Q02928 2/20 0.51
KEAP1 Q14145 1/20 0.50
FFAR1 O14842 3/20 0.47
ALOX5 P09917 2/20 0.47
APP P05067 1/20 0.47
ABCB1 P08183 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
CYP4Z1 Q86W10 1/20 0.45
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043506 0.92 CYP4F2 (0.55) TDP1CYP4F2CYP4A11ALOX5APP
SCHEMBL3175580 0.87 CYP4F2 (0.57) TDP1CYP4F2CYP4A11KEAP1FFAR1
Ethyl 3-Phenylpropanoate SCHEMBL311047 0.87 TDP1 (0.68) TDP1CYP4F2CYP4A11KEAP1FFAR1
Ethyl 3-Phenylpropanoate SCHEMBL8614481 0.86 TDP1 (0.66) TDP1CYP4F2CYP4A11KEAP1FFAR1
Ethyl 3-Phenylpropanoate SCHEMBL27562389 0.84 CYP4F2 (0.66) TDP1CYP4F2CYP4A11KEAP1FFAR1
Ethyl 3-Phenylpropanoate SCHEMBL304816 0.83 TDP1 (0.75) TDP1CYP4F2CYP4A11KEAP1ALOX5
SCHEMBL1207329 0.83 KEAP1 (0.61) KEAP1FFAR1FFAR4
SCHEMBL1587300 0.81 CYP4F2 (0.74) TDP1CYP4F2CYP4A11KEAP1FFAR1
SCHEMBL4425984 0.81 CYP4F2 (0.64) TDP1CYP4F2CYP4A11ALOX5APP
Ethyl 3-Phenylpropanoate SCHEMBL7440447 0.81 TDP1 (0.72) TDP1CYP4F2CYP4A11KEAP1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713149-B1 Electrophotographic photoreceptor using charge transporting copolyester FUJI XEROX CO LTD (JP) 2000-08-23 EP disclosed
EP-0686879-B1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO LTD (JP) 2000-05-24 EP disclosed
US-5770339-A DICARBOXYLIC ACID COMPONENT CONTAINS ONE OR TWO TERTIARY AMINE GROUPS, IMPROVED SOLUBILITY, FILM FORMATION, CONTROLLABLE IONIZATION POTENTIAL FUJI XEROX CO., LTD. (JP) 1998-06-23 US disclosed
US-5731118-A Charge transporting random copolyester resin, process for producing the same and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1998-03-24 US disclosed
US-5604064-A USEFUL IN ELECTROPHOTOGRAPHIC PHOTORECEPTORS FUJI XEROX CO., LTD. (JP) 1997-02-18 US disclosed
EP-0713149-A1 Organic electronic device using charge transporting copolyester FUJI XEROX CO., LTD. (JP) 1996-05-22 EP disclosed
EP-0687958-A1 Charge-transporting polymer and organic electron device using same FUJI XEROX CO., LTD. (JP) 1995-12-20 EP disclosed
EP-0686879-A1 Charge-transporting polymer and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1995-12-13 EP disclosed