Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043736 | 1.00 | SMYD3 (0.42) | SMYD3 | |
| SCHEMBL8044025 | 0.82 | SMYD3 (0.38) | SMYD3 | |
| SCHEMBL8044030 | 0.82 | SMYD3 (0.38) | SMYD3 | |
| SCHEMBL30812423 | 0.79 | EPHX2 (0.35) | — | |
| SCHEMBL7496968 | 0.76 | MEN1 (0.34) | — | |
| SCHEMBL7417543 | 0.73 | MEN1 (0.33) | — | |
| SCHEMBL8048468 | 0.71 | HPGD (0.41) | SMYD3 | |
| SCHEMBL30147123 | 0.66 | EPHX2 (0.38) | — | |
| SCHEMBL6963805 | 0.65 | ALDH1A1 (0.46) | — | |
| Bicarbonate SCHEMBL15225846 | 0.64 | TSHR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121280-A | Azabicyclic rotomase inhibitors | PFIZER INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0947506-A1 | 2-Aza-bicyclo[2.2.1]heptane derivatives and their use as rotamase inhibitors | Pfizer Products Inc. (US) | 1999-10-06 | — | — | EP | disclosed |