Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046739 | 0.84 | TACR1 (0.35) | SMYD3PREP | |
| SCHEMBL8043206 | 0.75 | GRIN2B (0.39) | SMYD3PREP | |
| SCHEMBL8046810 | 0.75 | SMYD3 (0.35) | MEN1KMT2ASMYD3ALDH1A1PREP | |
| SCHEMBL8043737 | 0.71 | SMYD3 (0.42) | SMYD3 | |
| SCHEMBL8043736 | 0.71 | SMYD3 (0.42) | SMYD3 | |
| SCHEMBL8044025 | 0.66 | SMYD3 (0.38) | MEN1KMT2ASMYD3TSHRALDH1A1 | |
| SCHEMBL8044030 | 0.66 | SMYD3 (0.38) | MEN1KMT2ASMYD3TSHRALDH1A1 | |
| SCHEMBL4572679 | 0.65 | HPGD (0.55) | HPGDRECQLMEN1KMT2ACYP1A2 | |
| SCHEMBL4572677 | 0.65 | HPGD (0.55) | HPGDRECQLMEN1KMT2ACYP1A2 | |
| SCHEMBL4572675 | 0.63 | HPGD (0.52) | HPGDRECQLMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121280-A | Azabicyclic rotomase inhibitors | PFIZER INC. (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0947506-A1 | 2-Aza-bicyclo[2.2.1]heptane derivatives and their use as rotamase inhibitors | Pfizer Products Inc. (US) | 1999-10-06 | — | — | EP | disclosed |