Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15309350 | 0.89 | DAPK1 (0.43) | AURKAAURKBTTRALDH1A1TSHR | |
| SCHEMBL10548795 | 0.86 | AURKA (0.47) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL2596490 | 0.84 | AURKA (0.46) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL30035234 | 0.84 | AURKA (0.46) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL5181911 | 0.84 | ALDH1A1 (0.41) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL9680157 | 0.82 | AURKA (0.47) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL27881048 | 0.81 | TTR (0.46) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL8164868 | 0.81 | ALDH1A1 (0.46) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL8755118 | 0.81 | AURKA (0.43) | AURKAAURKBTTRNQO1ALDH1A1 | |
| SCHEMBL11810695 | 0.79 | AURKA (0.42) | AURKAAURKBTTRNQO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013018071-A2 | FIBRE REACTIVE AZO REACTIVE COLORANTS CONTAINING TWO REACTIVE GROUPS OF THE VINYLSULFONE TYPE, PRODUCTION AND USE THEREOF | COLOURTEX INDUSTRIES LIMITED (IN) | 2013-02-07 | — | — | WO | disclosed |
| US-6046311-A | Water-soluble fiber-reactive dyes, preparation thereof and use thereof | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2000-04-04 | — | — | US | disclosed |
| EP-0962501-A2 | Mixtures of reactive dyes and their use for dyeing material containing hydroxy and/or carbonamide groups | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0416363-A2 | Modification of Polyarylenesulfides | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |
| EP-0093369-B1 | REACTIVE DYES | BAYER AG (DE) | 1986-07-23 | — | — | EP | disclosed |
| EP-0093369-A2 | Reactive dyes | BAYER AG (DE) | 1983-11-09 | — | — | EP | disclosed |
| EP-0001451-B1 | WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1981-09-23 | — | — | EP | disclosed |
| EP-0001614-A1 | Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation | CASSELLA Aktiengesellschaft (DE) | 1979-05-02 | — | — | EP | disclosed |
| EP-0001451-A1 | Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1979-04-18 | — | — | EP | disclosed |