SCHEMBL9680157

SCHEMBL9680157

Nc1ccc(S(=O)(=O)O)c(N)c1N

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.47
AURKB Q96GD4 1/20 0.47
TTR P02766 1/20 0.45
NQO1 P15559 1/20 0.40
ALDH1A1 P00352 6/20 0.39
TSHR P16473 3/20 0.39
NT5E P21589 2/20 0.39
HSD17B10 Q99714 4/20 0.38
GAA P10253 3/20 0.38
THRB P10828 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
RECQL P46063 2/20 0.38
MEN1 O00255 1/20 0.38
PKM P14618 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27881048 0.90 TTR (0.46) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL2596490 0.84 AURKA (0.46) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL30035234 0.84 AURKA (0.46) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL8043759 0.82 AURKA (0.44) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL10881186 0.82 AURKA (0.49) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL10548795 0.81 AURKA (0.47) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL8079054 0.80 AURKA (0.43) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL8082214 0.80 AURKA (0.43) AURKAAURKBTTRNQO1ALDH1A1
SCHEMBL32077 0.79 TTR (0.64) AURKAAURKBTTRALDH1A1TSHR
SCHEMBL10881024 0.79 AURKA (0.46) AURKAAURKBTTRNQO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872639-A Cement grinding-aid reinforcing agent and preparation method thereof 安徽海螺材料科技股份有限公司 2023-03-31 CN disclosed
CN-114890946-A Morpholine propyl group-containing [ (quinoline-4-yl) amino ] benzamide compound and preparation and application thereof 沈阳药科大学 2022-08-12 CN disclosed
CN-106944452-A For the apparatus and method for recycling period stripping solder metal in discarded Electrical and Electronic equipment 恩特格里斯公司 2017-07-14 CN disclosed
CN-106914470-A For the apparatus and method for recycling period stripping solder metal in discarded Electrical and Electronic equipment 恩特格里斯公司 2017-07-04 CN disclosed
US-5128455-A WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed
US-3985797-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3985796-A Hydroxylation of aromatic compounds UOP INC. (US) 1976-10-12 US disclosed
US-3931295-A Hydroxylation of aromatic compounds UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-01-06 US disclosed