Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MYOC | Q99972 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828028 | 0.91 | HSPB1 (0.47) | HSPB1ALDH1A1KDM4EHTTATM | |
| SCHEMBL28983411 | 0.83 | HSPB1 (0.51) | HSPB1ALDH1A1KDM4EHTTATM | |
| SCHEMBL7632959 | 0.81 | HSPB1 (0.66) | HSPB1ALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL20339398 | 0.79 | HSPB1 (0.51) | HSPB1ALDH1A1KDM4EHTTATM | |
| SCHEMBL29527846 | 0.79 | HSPB1 (0.51) | HSPB1ALDH1A1KDM4EHTTATM | |
| SCHEMBL9497268 | 0.79 | HSPB1 (0.51) | HSPB1ALDH1A1KDM4EHTTATM | |
| SCHEMBL30176238 | 0.79 | HTT (0.58) | HSPB1ALDH1A1KDM4EHTTATM | |
| SCHEMBL1979596 | 0.77 | HSPB1 (0.53) | HSPB1ALDH1A1KDM4EHTTATM | |
| SCHEMBL31634156 | 0.77 | ALDH1A1 (0.50) | HSPB1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL5082634 | 0.77 | ALDH1A1 (0.66) | HSPB1ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093790-A | POLYIMIDE COATING MATERIAL COMPRISING MONOMERS HAVING PHENOLIC DIETHER AND TERT-BUTYL MOIETIES; THERMAL AND PHYSICAL PROPERTIES | NATIONAL SCIENCE COUNCIL (TW) | 2000-07-25 | — | — | US | disclosed |