Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033685 | 0.83 | LMNA (0.48) | LMNATSHRSMN1; SMN2MAPTMEN1 | |
| SCHEMBL8047837 | 0.82 | APP (0.43) | LMNAMAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL8044621 | 0.73 | MEN1 (0.40) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL5958784 | 0.71 | CYP19A1 (1.00) | CYP19A1LMNATSHRVCAM1SMN1; SMN2 | |
| SCHEMBL212845 | 0.68 | CYP19A1 (0.81) | CYP19A1LMNATSHRVCAM1SMN1; SMN2 | |
| SCHEMBL8542885 | 0.68 | LMNA (0.50) | LMNATSHRSMN1; SMN2MAPTMEN1 | |
| SCHEMBL9789477 | 0.66 | CYP19A1 (0.77) | CYP19A1LMNATSHRVCAM1SMN1; SMN2 | |
| SCHEMBL16541066 | 0.66 | CYP19A1 (0.77) | CYP19A1LMNATSHRVCAM1SMN1; SMN2 | |
| SCHEMBL9789472 | 0.66 | CYP19A1 (0.77) | CYP19A1LMNATSHRVCAM1SMN1; SMN2 | |
| SCHEMBL29395454 | 0.66 | CYP19A1 (0.77) | CYP19A1LMNATSHRVCAM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |