Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043920 | 0.82 | CYP19A1 (0.52) | MAPTALDH1A1POLBL3MBTL1LMNA | |
| SCHEMBL8033685 | 0.80 | LMNA (0.48) | MAPTALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL9860671 | 0.71 | POLB (0.51) | MAPTALDH1A1POLBGFERCA12 | |
| SCHEMBL6423919 | 0.71 | CA1 (0.67) | APPMAPTALDH1A1POLBLMNA | |
| SCHEMBL28198 | 0.71 | CA1 (0.67) | APPMAPTALDH1A1POLBLMNA | |
| SCHEMBL8044621 | 0.70 | MEN1 (0.40) | ALDH1A1 | |
| SCHEMBL4877279 | 0.70 | ALDH1A1 (0.38) | MAPTALDH1A1GFERGAAKDM4E | |
| SCHEMBL8044178 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 | |
| Water SCHEMBL28670631 | 0.69 | CA1 (0.64) | APPMAPTALDH1A1POLBLMNA | |
| SCHEMBL27752664 | 0.68 | ALDH1A1 (0.65) | APPALDH1A1LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |