Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 5/20 | 0.36 |
| ▸ | ATP4B | P51164 | 5/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 8/20 | 0.34 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.32 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.32 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.32 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.32 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.32 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.32 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063180 | 0.79 | CSNK1E (0.34) | ATP4AATP4BCSNK1ECSNK1G3NPY5R | |
| SCHEMBL10626657 | 0.77 | KDM4E (0.51) | CSNK1ECSNK1G3HTT | |
| SCHEMBL6994892 | 0.76 | PSMB8 (0.46) | ATP4AATP4BCSNK1ECSNK1G3NPY5R | |
| SCHEMBL9688607 | 0.73 | CSNK1E (0.32) | ATP4AATP4BCSNK1ECSNK1G3NPY5R | |
| SCHEMBL10626621 | 0.71 | KDM4E (0.46) | CSNK1ECSNK1G3HTT | |
| SCHEMBL8560478 | 0.70 | CSNK1E (0.38) | ATP4AATP4BCSNK1ECSNK1G3NPY5R | |
| SCHEMBL1193108 | 0.70 | ALDH1A1 (0.49) | GAAHTT | |
| SCHEMBL15553070 | 0.69 | FABP6 (0.49) | ATP4AATP4BCSNK1ECSNK1G3NPY5R | |
| SCHEMBL8265318 | 0.69 | MAPT (0.46) | ATP4AATP4BCSNK1ECSNK1G3NPY5R | |
| SCHEMBL577623 | 0.69 | GAA (0.57) | GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054589-A | Process for preparing 2-chloro-benzimidazole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |
| US-6028200-A | Process for preparing 2-chloro-benzimidazole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-22 | — | — | US | disclosed |
| EP-0893445-A1 | Process for the preparation of 2-chlorobenzimidazole derivatives | BAYER AG (DE) | 1999-01-27 | — | — | EP | disclosed |