Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 5/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039605 | 0.88 | CNR1 (0.41) | CNR1RXRANR4A2PTGS1 | |
| SCHEMBL8037711 | 0.84 | KDM4E (0.47) | CNR1RXRANR4A2KMOPDE4B | |
| SCHEMBL4007802 | 0.81 | ATM (0.40) | CNR1KMOPDE4BPDE4DSMN1; SMN2 | |
| SCHEMBL8038617 | 0.78 | ATM (0.52) | CNR1RXRANR4A2DHODHSMN1; SMN2 | |
| SCHEMBL8021755 | 0.77 | KDM4E (0.39) | CNR1RXRANR4A2KMOPDE4B | |
| SCHEMBL8038387 | 0.73 | KDM4E (0.46) | SMN1; SMN2 | |
| SCHEMBL4007805 | 0.70 | CNR1 (0.41) | CNR1KMOPDE4BPDE4DSMN1; SMN2 | |
| SCHEMBL8036895 | 0.70 | MAPT (0.40) | — | |
| SCHEMBL8034697 | 0.70 | MAPT (0.40) | — | |
| SCHEMBL8037264 | 0.69 | KDM4E (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |