Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052220 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8033692 | 0.85 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8043940 | 0.81 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8048777 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8043685 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8044786 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8043953 | 0.77 | TDP1 (0.47) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8045990 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8047577 | 0.77 | SMN1; SMN2 (0.45) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT | |
| SCHEMBL8033935 | 0.77 | HSD17B10 (0.47) | ALDH1A1LMNASMN1; SMN2HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |