Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666211 | 0.82 | POLB (0.46) | TSHRALDH1A1TDP1HSD17B10KDM4E | |
| SCHEMBL13497796 | 0.81 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9012929 | 0.80 | KDM4E (0.44) | TSHRALDH1A1ADRA2BTDP1HSD17B10 | |
| SCHEMBL20798388 | 0.80 | ALDH1A1 (0.42) | TSHRL3MBTL1ALDH1A1ADRA2BPTGS1 | |
| SCHEMBL8031008 | 0.79 | TSHR (0.39) | TSHRL3MBTL1ALDH1A1TDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9793148 | 0.78 | TSHR (0.38) | TSHRL3MBTL1ALDH1A1KDM4EMEN1 | |
| SCHEMBL24854029 | 0.77 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL29814301 | 0.77 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL2476416 | 0.77 | KDM4E (0.47) | TSHRL3MBTL1ALDH1A1HSD17B10GBA1 | |
| SCHEMBL3672546 | 0.76 | KDM4E (0.59) | TSHRL3MBTL1ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000076469-A1 | ONE STEP METHOD AND COMPOSITIONS FOR SIMULTANEOUSLY COLORING AND HIGHLIGHTING HAIR | REVLON CONSUMER PRODUCTS CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |