Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7104162 | 0.93 | KDM4E (0.46) | KDM4EGLATSHRL3MBTL1GBA1 | |
| SCHEMBL20837291 | 0.83 | NCF1 (0.44) | KDM4EL3MBTL1CHRM2USP2HTR1A | |
| SCHEMBL3073595 | 0.82 | CHRM2 (0.62) | KDM4EGLATSHRL3MBTL1GBA1 | |
| SCHEMBL27982786 | 0.81 | TSHR (0.55) | KDM4EGLATSHRL3MBTL1GBA1 | |
| SCHEMBL20232562 | 0.81 | ALDH1A1 (0.42) | KDM4EL3MBTL1CHRM2HTR1AADRA1D | |
| SCHEMBL741786 | 0.81 | CHRM2 (0.49) | KDM4ETSHRL3MBTL1CHRM2HTT | |
| SCHEMBL2219253 | 0.80 | CHRM2 (0.51) | KDM4EL3MBTL1CHRM2HTTHTR1A | |
| SCHEMBL7808713 | 0.79 | KDM4E (0.40) | KDM4EGLATSHRL3MBTL1GBA1 | |
| SCHEMBL20837292 | 0.78 | SMN1; SMN2 (0.46) | KDM4EALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL9793192 | 0.78 | KDM4E (0.39) | KDM4EGLATSHRL3MBTL1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3989920-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | Living Proof, Inc. (US) | 2022-05-04 | — | — | EP | claimed |
| EP-1707242-A1 | Oxidative hair colouring composition comprising 1,5- and /or 2,7-dihydroxy naphthalene and at least one further coupling agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-10-04 | — | — | EP | claimed |
| EP-3989920-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | Living Proof, Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| US-10738056-B2 | Pyrazolopyrimidinone compounds and uses thereof | ADURO BIOTECH INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-20190119285-A1 | PYRAZOLOPYRIMIDINONE COMPOUNDS AND USES THEREOF | CHINOOK THERAPEUTICS, INC. | 2019-04-25 | — | — | US | disclosed |
| WO-2019055750-A1 | PYRAZOLOPYRIMIDINONE COMPOUNDS AND USES THEREOF | Aduro Biotech, Inc. (US) | 2019-03-21 | — | — | WO | disclosed |
| EP-1707242-B1 | Oxidative hair colouring composition comprising 1,5- and /or 2,7-dihydroxy naphthalene and at least one further coupling agent | HENKEL AG & CO KGAA (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2008049651-A1 | PERFORMANCE-ENHANCED COSMETIC COMPOSITIONS WITH PURINE AND/OR PURINE DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2008-05-02 | — | — | WO | disclosed |
| EP-0858796-B2 | Oxidative hair dye | WELLA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| EP-1707242-A1 | Oxidative hair colouring composition comprising 1,5- and /or 2,7-dihydroxy naphthalene and at least one further coupling agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1707242-A1 | Oxidative hair colouring composition comprising 1,5- and /or 2,7-dihydroxy naphthalene and at least one further coupling agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-0910330-B1 | HAIR DYE COMPOSITIONS AND PROCESS | REVLON CONSUMER PROD CORP (US) | 2003-10-22 | — | — | EP | disclosed |
| US-6596035-B2 | Hair colorant consists of 1-10% inorganic persulfate, (b) 1-20% hydrogen peroxide, (c) 0.001-20% of at least one primary intermediate, one or more surfactants and optionally, a coupler for formation of oxidation dye | REVLON CONSUMER PRODUCTS CORPORATION | 2003-07-22 | — | — | US | disclosed |
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| EP-0858796-B1 | Oxidative hair dye | WELLA AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-20010039685-A1 | One step method and compositions for simultaneously coloring and highlighting hair | REVLON CONSUMER PRODUCTS CORPORATION (US) | 2001-11-15 | — | — | US | disclosed |
| WO-2001045657-A1 | LIQUID CRYSTALLINE PEROXIDE COMPOSITIONS AND METHOD FOR COLORING AND/OR BLEACHING HAIR | REVLON CONSUMER PRODUCTS CORPORATION (US) | 2001-06-28 | — | — | WO | disclosed |
| US-6238653-B1 | ORGANIC, AMPHIPHILIC, SURFACE ACTIVE INGREDIENT CAPABLE OF INTERACTING WITH THE WATER PHASE AND THE OIL PHASE TO FORM LYOTROPIC LIQUID CRYSTALS CONTAINING SAID WATER PHASE INGREDIENTS | REVLON CONSUMER PRODUCTS CORPORATION | 2001-05-29 | — | — | US | disclosed |
| EP-0858796-A2 | Oxidative hair dye | Wella Aktiengesellschaft (DE) | 1998-08-19 | — | — | EP | disclosed |
| CN-1134275-A | Composition for oxidation dyeing of keratinous fibres, and dyeing process using this composition | OREAL (FR) | 1996-10-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738056-B2 | Pyrazolopyrimidinone compounds and uses thereof | NLRP3, NLRP1, P2RX7 | KDM4E 1922/4885GLA 3087/4885TSHR 4008/4885 |
| US-20030110577-A1 | Novel p-aminophenols and colorants containing said compounds | ALPP, GSTP1, GPX4 | KDM4E 1805/4885GLA 1909/4885TSHR 1892/4885 |
| US-20010039685-A1 | One step method and compositions for simultaneously coloring and highlighting hair | SHH, PRDX3, GSR | KDM4E 3087/4885GLA 1132/4885TSHR 636/4885 |
| US-20190119285-A1 | PYRAZOLOPYRIMIDINONE COMPOUNDS AND USES THEREOF | NLRP3, NLRP1, P2RX7 | KDM4E 1922/4885GLA 3087/4885TSHR 4008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.