SCHEMBL8044183

SCHEMBL8044183

Oc1ccc(-c2ncnc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.53
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
NTSR1 P30989 1/20 0.47
GFER P55789 1/20 0.47
ESR2 Q92731 3/20 0.46
ESR1 P03372 2/20 0.46
HSP90AA1 P07900 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
ADORA1 P30542 1/20 0.43
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
USP7 Q93009 1/20 0.41
MAPT P10636 2/20 0.41
CNR1 P21554 1/20 0.41
NR2F2 P24468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8911208 0.97 ALOX5 (0.56) ALOX5KMT2AMEN1NTSR1GFER
SCHEMBL494006 0.87 ALOX5 (0.60) ALOX5KMT2AMEN1NTSR1GFER
SCHEMBL29740228 0.87 ALOX5 (0.60) ALOX5KMT2AMEN1NTSR1GFER
SCHEMBL27881592 0.85 TSHR (0.58) KMT2AMEN1NTSR1ADORA3ALOX15
SCHEMBL4438569 0.85 ESR1 (0.46) ALOX5KMT2AMEN1GFERESR2
SCHEMBL2351351 0.84 MEN1 (0.50) KMT2AMEN1ESR2ESR1ALOX15
SCHEMBL21414949 0.83 ESR2 (0.47) ALOX5KMT2AMEN1GFERESR2
SCHEMBL1243192 0.83 ALOX5 (0.64) ALOX5KMT2AMEN1NTSR1GFER
SCHEMBL29649804 0.83 ALOX5 (0.64) ALOX5KMT2AMEN1NTSR1GFER
SCHEMBL29649729 0.83 ALOX5 (0.64) ALOX5KMT2AMEN1NTSR1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199638-A Process for preparing 2, 4-di (biphenyl-4-yl) -6- (2, 4-dihydroxyphenyl) -1,3, 5-triazine 江苏丹霞新材料有限公司 2023-06-02 CN claimed
CN-116199638-A Process for preparing 2, 4-di (biphenyl-4-yl) -6- (2, 4-dihydroxyphenyl) -1,3, 5-triazine 江苏丹霞新材料有限公司 2023-06-02 CN disclosed
CN-116199638-A Process for preparing 2, 4-di (biphenyl-4-yl) -6- (2, 4-dihydroxyphenyl) -1,3, 5-triazine 江苏丹霞新材料有限公司 2023-06-02 CN disclosed
CN-116199638-A Process for preparing 2, 4-di (biphenyl-4-yl) -6- (2, 4-dihydroxyphenyl) -1,3, 5-triazine 江苏丹霞新材料有限公司 2023-06-02 CN disclosed
US-6013704-A A STABILIZER AGAINST THE DAMAGING ACTION OF LIGHT, OXYGEN AND HEAT; PROTECTIVE COATINGS FOR PHOTOGRAPHIC MATERIAL CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-11 US disclosed