SCHEMBL4438569

SCHEMBL4438569

Oc1ccc(-c2ncnc(-c3ccc(O)cc3O)n2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.46
ESR2 Q92731 5/20 0.46
ALOX5 P09917 1/20 0.43
TYR P14679 3/20 0.43
NPC1 O15118 4/20 0.41
MAPT P10636 3/20 0.40
ALDH1A1 P00352 2/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
RUNX1 Q01196 1/20 0.40
CBFB Q13951 1/20 0.40
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KMT2A Q03164 2/20 0.39
GFER P55789 1/20 0.39
HSP90AA1 P07900 1/20 0.39
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21414949 0.91 ESR2 (0.47) ESR1ESR2ALOX5NPC1MAPT
SCHEMBL8911208 0.88 ALOX5 (0.56) ESR1ESR2ALOX5NPC1MAPT
SCHEMBL547889 0.86 NPC1 (0.52) ESR1ESR2ALOX5TYRNPC1
SCHEMBL29625130 0.86 NPC1 (0.52) ESR1ESR2ALOX5TYRNPC1
SCHEMBL2354543 0.85 ESR2 (0.42) ESR1ESR2NPC1MAPTALDH1A1
SCHEMBL8044183 0.85 ALOX5 (0.53) ESR1ESR2ALOX5MAPTKMT2A
SCHEMBL2351351 0.85 MEN1 (0.50) ESR1ESR2MAPTGAAHTT
Water SCHEMBL8683475 0.84 NPC1 (0.50) ESR1ESR2ALOX5TYRNPC1
SCHEMBL8908993 0.83 ESR2 (0.38) ESR1ESR2NPC1MAPTALDH1A1
SCHEMBL4206563 0.83 ALOX5 (0.43) ESR1ESR2ALOX5TYRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2849716-B1 EASILY FORMULATED ZINC OXIDE POWDER BASF SE (DE) 2018-07-11 EP disclosed
US-8865620-B2 Heat-sensitive coating compositions based on resorcinyl triazine derivatives DATALASE, LTD. (GB) 2014-10-21 US disclosed
US-20110311786-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES DATALASE LTD 2011-12-22 US disclosed
EP-2121853-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES BASF SE (DE) 2009-11-25 EP disclosed
WO-2008110487-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES BASF SE (CH) 2008-09-18 WO disclosed
EP-0682680-B1 ELECTRO COAT/BASE COAT/CLEAR COAT FINISHES STABILIZED WITH s-TRIAZINE UV ABSORBERS CIBA SC HOLDING AG (CH) 2004-03-24 EP disclosed
EP-1109792-A1 PROCESS FOR MAKING 2- (2,4- DIHYDROXYPHENYL) OR 2- (2,4- DIALKOXYPHENYL)- 4,6- BISARYL- 1,3,5- TRIAZINES CYTEC TECHNOLOGY CORP. (US) 2001-06-27 EP disclosed
WO-2000014077-A1 PROCESS FOR MAKING 2- (2,4- DIHYDROXYPHENYL) OR 2- (2,4- DIALKOXYPHENYL)- 4,6- BISARYL- 1,3,5- TRIAZINES CYTEC TECHNOLOGY CORP. (US) 2000-03-16 WO disclosed
US-5476937-A Photostability, protective coatings CIBA-GEIGY CORPORATION (US) 1995-12-19 US disclosed
EP-0682680-A1 ELECTRO COAT/BASE COAT/CLEAR COAT FINISHES STABILIZED WITH s-TRIAZINE UV ABSORBERS Ciba SC Holding AG (CH) 1995-11-22 EP disclosed
US-5354794-A Antipeeling; for automobiles CIBA-GEIGY CORPORATION (US) 1994-10-11 US disclosed
WO-1994018278-A2 ELECTRO COAT/BASE COAT/CLEAR COAT FINISHES STABILIZED WITH s-TRIAZINE UV ABSORBERS CIBA-GEIGY AG (CH) 1994-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110311786-A1 HEAT-SENSITIVE COATING COMPOSITIONS BASED ON RESORCINYL TRIAZINE DERIVATIVES OR10J3, NR3C2, NR1H2 ESR1 495/4885ESR2 476/4885ALOX5 2469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.